March Madness Sweet Sixteen Gambling Guide 2023

The best March Madness Sweet Sixteen gambling sites are quick to release betting lines after the second round concludes. You […]

Last Updated 10th, March 2023

The best March Madness Sweet Sixteen gambling sites are quick to release betting lines after the second round concludes. You will find competitive odds on a wide array of markets, along with large bonuses. Some sites offer exciting features such as live NCAAB streaming too.

This guide highlights the top 10 sportsbooks for betting on the Sweet 16 round of March Madness. We will help you find the right betting site for your needs. You will also discover the most popular betting options, the largest bonuses and our top Sweet 16 betting tips, so keep reading to learn more.



Our full March Madness betting guide provides a detailed breakdown of how to bet on the NCAA Tournament in detail. You will learn how to sign up, make a deposit, claim the sign-up bonus and place bets at the top sportsbooks.

Reviews of the Best March Madness Sweet 16 Sportsbooks

The best offshore sportsbooks for March Madness are all trustworthy sites that pay out in full and on time. However, they have different strengths and specialties, so read on to learn more about them and find your ideal fit.



How to Place Bets on March Madness Sweet 16 Teams

If you would like to place bets online on March Madness Sweet Sixteen teams, just follow the steps provided:

Step 1: Visit the Best March Madness Sportsbook

Head over to BetOnline, the best all-round sportsbook for NCAA basketball betting, and then hit the “Join” button. The sign-up form will appear on the screen.

BetOnline Homepage

Step 2: Fill in the Form

The sign-up form at this March Madness Sweet 16 online gambling site asks for some simple personal and contact details. Fill it in and click “Create Account.”

BetOnline Registration Form

Step 3: Make a Deposit

You will not need to go through a KYC process, so simply click the green button to open the cashier and fund your account for the first time. The funds will arrive straight away, and this March Madness Sweet Sixteen gambling site will then release your bonus funds.

Step 4: Choose a March Madness Bet

It is now time for you to place March Madness Sweet 16 bets. Select basketball from the main sports displayed, choose NCAA and find a betting option you like. Click on that pick to add it to your betslip, choose a bet amount and click again to place the wager.

BetOnline March Madness Wager

2023 March Madness Sweet 16 Odds

March Madness Sweet 16 betting odds are displayed in the American format at most online sportsbooks. That means they start with a plus or a minus. This is an example:

  • Arizona to beat Houston (-125)
  • Houston to beat Arizona (+105)

Odds that start with a minus tell you the dollar amount you would need to wager to win $100. A $125 bet at -125 on Arizona would net you $100.

When they begin with a plus, the numbers show the net profit available on a $100 bet. A $100 wager at +105 would earn you a $105 profit.

Types of March Madness Sweet 16 Bets & Features

You will be offered a wide range of betting options and features at the leading March Madness Sweet Sixteen gambling sites. These are the most common markets and features to look out for:

Moneyline Bets

This is the simplest option for anyone that is interested in placing bets on March Madness Sweet Sixteen teams. You simply need to predict who will win the game. For example, you might find odds of -145 on Miami to beat Iowa State, and odds of +125 on Iowa State to beat Miami. As explained above, the odds highlight the potential net profit available, so you can make your plays accordingly.

Spread Betting

This is the most common betting option on the Sweet 16. The sportsbooks give the stronger NCAAB team (the favorite in the moneyline odds) a handicap, which creates the spread and allows them to offer similar odds on either team covering it. If we stick with the above example, you would expect odds of -110 on Miami -2.5 and -110 on Iowa State +2.5.


This is an over/under bet on the number of points that will be scored in a college basketball game. For example, you might be offered odds of -110 on over 141.5 points and -110 on under 141.5 points. Most sportsbooks offer alternative lines too, plus totals for each half and each team.

Prop Bets

Props focus on players, teams and game events. Examples of props for anyone that wants to place bets on March Madness Sweet 16 could include over/under on a player’s total points, a prediction on whether a game will go to overtime or the first team to reach 20 points.


Parlays are combination bets featuring at least two picks on separate March Madness games. For example, you could bet on three different teams to cover the spread. All three would need to cover for the parlay to win, and you would then look forward to a large payout, as the odds on each pick are multiplied together to calculate the overall profit.

Live Betting

You can place an in-play March Madness bet on Sweet Sixteen teams at the best online sportsbooks. They update the spread, the moneyline, the totals and various prop markets during the game to reflect the score.

Live Streaming

Sportsbooks such as BetOnline offer live streaming of March Madness Sweet 16 games. That allows you to watch the action and bet on it in one place.

March Madness Sweet 16 Predictions

It is important to conduct thorough research before betting on the Sweet 16. By this stage of the NCAA Tournament, you will have a wealth of data at your disposal from the previous two rounds. This can help you make educated Sweet 16 predictions.

March Madness Sweet 16 Favorites

Favorites normally have a strong record in the Sweet 16, but a couple of No. 1 seeds crashed out last year. We will provide our picks to help you place bets online on March Madness Sweet Sixteen. Return to this page when the second round has concluded and the Sweet 16 is about to get underway for picks and predictions.

March Madness Sweet 16 Upsets

Saint Peter’s continued their famous run of upsets by securing a hard-fought 67-64 win against Purdue in the Sweet 16 last year. North Carolina also upset UCLA, Arkansas eliminated Gonzaga – the pre-tournament favorite – and Houston pulled off yet another upset against Arizona.

Will underdogs enjoy a similar level of success this time around? Head back to this page ahead of the Sweet 16 for our picks and predictions.

The Best March Madness Betting Site

BetOnline is the best March Madness Sweet 16 online gambling site. It will release its lines quickly after the second round concludes, and the odds are always competitive. You can choose from a wide selection of alternative NCAAB lines and props, with broad limits to suit all bettors.

If you register today, you will earn up to $1,000 in bonus credits. It will also give you a risk-free live bet, and there are other promos to claim too. BetOnline offers live March Madness streaming, excellent customer service and quick, secure payouts. Just click the button below to redeem the welcome bonus and create your account.

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