Methylation is a chemical process in the body where methyl groups (CH3) are added to certain proteins to aid in their assimilation. This process is crucial for some biological functions because it makes the proteins in question easier to absorb. Methylated multivitamins are easier for the body to process than regular multivitamins.
In this article, we’re going to introduce you to some of the best methylated multivitamin options, starting with Double Wood Methylated Multivitamin. We’ll also show why they might be a better choice than a regular multivitamin.
| Rank | Site | Award |
| 1 | Double Wood Methylated Multivitamin | Best methylated multivitamin overall |
| 2 | Akasha Naturals Methylation Support | Best methylated multivitamin for men |
| 3 | Ancient Nutrition Multivitamin Immune | Best methylated multivitamin for women |
| 4 | Solaray Spectro Multivitamin | Best for antioxidant protection |
Methylated vitamins have gained attention for their enhanced bioavailability, particularly for individuals with specific genetic variations. But what are they, and why do they matter?
As we mentioned, a methylated vitamin has a methyl group (CH3) attached to its chemical structure. This process makes the vitamin more active, making it easier for the body to absorb.
Methylated vitamins are in a form that can be immediately used by the body. Regular vitamins need to be broken down by the body’s chemical processes first before they can be utilized.
Those with genetic variations like the methylenetetrahydrofolate reductase (MTHFR) gene can have difficulty converting folate to its more active and usable form. This is important because folate is instrumental in changing the amino acid homocysteine to the more usable amino compound known as methionine. Methylated vitamins help individuals with the MTHFR gene break down folate more effectively.
In the following sections, we’ll carefully review each brand on our list, exploring each company’s background, why the products stand out, their promotional offerings, and how to reach their support team.
This popular brand that uses the slogan “rooted in science, grounded in transparency,” Double Wood Supplements has been providing top-grade vitamins since 2013 when twin brothers Reese and Evan Wood founded the company.
This methylated multivitamin contains all the B vitamins essential for optimum absorption and cellular synthesis. These include activated forms of B6, folic acid, B12, and TMG, a methylated amino acid.
All of the above play essential roles in cellular maintenance and energy production, ensuring that your body receives these essential nutrients in their most accessible and effective forms, which ultimately contributes to your overall health and well-being.
Double Wood is also 100% transparent, providing the certificate of analysis (COA) and all third-party testing results on their website. The multivitamin is also gluten-free and non-GMO, appealing to health-conscious consumers and those following a structured diet program.
A single purchase of a 120-capsule bottle sells for $29.95. Subscribers pay $23.96 per bottle and save 27% on a double pack and 29% on a triple pack. Plus, there’s a 30-day refund policy on your first bottle and free shipping on all U.S. orders.
Double Wood customer support is available via email, an on-site contact form, and via phone at 570-437-0203.
Akasha Naturals, an off-shoot of the Akasha Center for Integrative Medicine, was founded in 2002 by Dr. Edison de Mello. As an extension of the Center, the Akasha Naturals brand is all about empowering you to take control of your health in a holistic, integrated way.
Methylation is a process that cells use to make biochemical conversions to protect, repair, and enhance the workings of our immune system. This comprehensive Akasha Naturals formula features all the B vitamins involved in this cellular process in their most assimilable and effective biochemical forms.
This includes calcium L-5 methyltetrahydrofolate, N-acetyl-L-cysteine, methylated B6 and B12 vitamins, betaine HCI, and added manganese, zinc, and molybdenum.
In layman’s terms, these nutrients help to assist cellular repair, maintain a healthy immune system, produce glutathione, the body’s primary antioxidant, and so much more.
A one-time purchase of a 120-capsule bottle of Methylation Support costs $57.25. Free shipping is available until April 31, 2025.
You can contact Akasha Naturals Support via online form, email, or phone at 310-451-7775.
Believing in the human body’s potential for high performance and wanting to establish a support system for that, Ancient Nutrition was founded in 2016 by Jordan Rubin and Dr. Josh Axe. Since then, products like their Multivitamin Immune have been making life a little healthier for all of us.
Containing 21 vitamins and minerals (like magnesium, zinc, and iron), more than a half-dozen superfoods, plus beef liver and wild hake roe, Ancient Nutrition’s Multivitamin Immune delivers dense and easily accessible nutrition.
As a result, you can depend on the highest level of support for optimum immune health, a healthy stress response, and superior cardiovascular and bone health. It also helps to elevate cognitive function.
A one-time purchase of a 90-capsule bottle of Multivitamin Immune costs $49.95. Subscribers save 15% plus free delivery.
Customer service can be reached via email or text. You can also phone 1-855-803-1275 between 7 a.m. and 6 p.m. CST Monday through Friday and 8 a.m. and 4 p.m. CST Saturday.
Solaray was established in 1973 by Jim Beck, who aimed to seek natural solutions for his physical and mental health issues. From the brand’s first homemade formulations, it grew to commercialize its own herbal blends and supplements.
Spectro Multivitamin showcases 6 methylated multivitamins, namely K, A, C, B, E, and D. What’s more, it also includes herbal extracts, digestive enzymes, electrolytes, and minerals (such as calcium, iodine, and magnesium).
Solaray designed this supplement to protect your body from free radicals, thanks to its potent antioxidants. It also promises to support digestion and boost energy levels. Better yet, it’s lab-verified and made from a whole food base.
A single 360-capsule bottle currently costs $52.09. Yet, you can save 10% if you subscribe to monthly shipping.
You may contact Solaray via email, website contact form, or phone at 1-877-505-1777.
Choosing the right methylated multivitamin involves understanding your needs and the nuances of these specialized supplements. Here’s a breakdown of key considerations:
Methylated vitamins are not the norm in the supplement business. That means it is important to check the label of what you’re buying to make sure the methylated B vitamins you’re getting are in their most natural and easily absorbable form. You also need to check how all the ingredients included are sourced and that they have been verified by third-party testing.
Methylated vitamins are naturally occurring forms of vitamins found in whole food sources. Synthetic vitamins are much less effective because they are created in the laboratory and designed to mimic the quality of naturally occurring vitamins. They may also carry a higher risk of side effects.
Nature is a continually interactive and cooperative environment where multiple life forms support and enrich each other. When you buy any methylated vitamin, make sure that you get not only the necessary B vitamins in their purest forms but also other essential supplements and nutrients like zinc and magnesium. Also, don’t forget to eat a balanced diet.
Third-party testing by an impartial and non-vested organization is important to ensure that you’re getting the purest and highest-quality nutrients available, not just a well-written line of advertising from the manufacturer.
>>Buy Double Wood Methylated Multivitamin here
Methylation is a crucial biochemical process that impacts many bodily functions, from DNA synthesis to neurotransmitter production. Methylated nutrients play a vital role in supporting this process. Some key players include:
Also known as methylcobalamin, methylated B12 helps produce red blood cells, supports brain health and nerve health, lowers homocysteine levels, and increases cognitive functioning.
Also known as L-5-MTHF or l-methylfolate, methylfolate (vitamin B9) is essential for healthy conception in women, fetal development, DNA formation, prevention of neural tube defects, and more. In men, methylfolate can aid in improving heart health and balancing iron levels [1].
Also known as PLP, this is an active form of vitamin B6 that is essential for amino acid metabolism. It is also necessary for the production of neurotransmitters like serotonin and dopamine, as well as hemoglobin synthesis and proper immune functioning [2] [3].
Also called R5P, riboflavin is a form of vitamin B2. It is instrumental in metabolizing energy and assisting in cell growth development. It also plays an important role in oxidizing omega fatty acids and carbohydrates, producing DNA and RNA, and lowering glutathione levels [4].
Take a look at other nutrients that can boost your wellness:
>>Buy Double Wood Methylated Multivitamin here
Check out some of the perks that you might experience if you take methylated vitamins at the right dosage per day:
Here are some of the folks who may benefit from methylated vitamins:
Now, let’s see what actual users had to say about their experiences using the various methylated multivitamin brands we’ve reviewed.
On the website, one customer, Yaaqoub G, praised Double Wood Methylated Multivitamin for supporting his active lifestyle, even into his 60s. However, another customer, Liz, mentioned an unpleasant aftertaste that sticks around longer than she’d like [7].
One customer wrote on the official site that she felt Akasha was the best. Before she started using it regularly, she was sick all the time. Meanwhile, another customer appreciated the benefits but wished it had fewer extra ingredients [8].
One reviewer on Trustpilot, Linda, declared that she has been a loyal customer of Ancient Nutrition for many years and feels their products are absolutely fabulous [9]. However, Susan was not satisfied, stating that she found the taste unpleasant and that it didn’t dissolve well [10].
Redditor DaBonerChamp shared in r/Fitness that most of the supplements he’s tried have worked fine, including Solaray Spectro Multivitamin [11]. On the other hand, in r/Supplements, rachs1988 described Solaray as a good, but not excellent, brand since she feels the formula can be further improved.
>>Buy Double Wood Methylated Multivitamin here
Here are some questions that customers are asking about the best methylated multivitamin brands.
A methylated multivitamin has a methyl group (CH3) attached to the chemical structures of the various vitamins it contains. This process makes the vitamins included in the supplement more active, making it easier for the body to absorb them.
Because the body more easily absorbs the methylated form of a vitamin, they can be better for some individuals, such as:
You should always consult your doctor before taking any supplement. Still, if any of the following apply to you, it is possible that you need a methylated multivitamin:
No, the Olly company does not manufacture any methylated vitamin products.
Methylated vitamins should be avoided by the following groups of people:
The body absorbs methylated multivitamins more easily, but since everyone is different, especially those with potential vitamin deficiency, it would be wise to talk to your physician before taking them daily.
Yes, there are methylated multivitamins designed to support children’s nutritional needs. They are often marketed to parents as kids multivitamins to ensure optimal nutrient absorption for their children. Ask for advice from a pediatrician or your healthcare provider before giving any new vitamin or supplement to a child.
Now that you know more about methylated multivitamins and how they can make it easier for the body to absorb essential B nutrients, what do you think?
If it seems like a methylated multivitamin would be helpful, you should contact your doctor and see if they think it would be right for you.
All of the supplements we’ve suggested, including our top pick, Double Wood Methylated Multivitamin, are of the highest quality. They use cutting-edge science and the best ingredients, so they’re worth considering.
Happy hunting and good health!
>>Buy Double Wood Methylated Multivitamin here
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