Ognen Dimovski

Last Updated: Jul 01, 2025
Does Nugenix Work? An Honest Review of the Popular Testosterone Booster

Does Nugenix work to deliver on its promise of renewed energy, strength, and vitality? Since its launch back in 2012, Nugenix has positioned itself as a go-to testosterone booster for men looking to reclaim their youthful edge.

In this review, we’ll break down what’s inside Nugenix, how it’s supposed to work, potential benefits and side effects, and what real users have to say. Let’s find out if this popular supplement lives up to the hype or falls flat.

What Is Nugenix?

Nugenix is a line of male health products primarily focused on helping men restore healthy levels of free testosterone to increase their energy, strength, endurance, and libido.

Nugenix supplements are made from natural ingredients, such as vitamins, minerals, and various plant-based nutrients.

Key Ingredients in Nugenix

What determines the answer to “Does Nugenix work?” is what’s inside the formulas. Are you interested in knowing how to increase testosterone with supplements? Check out the main ingredients of Nugenix T-boosting supplements!

Testofen

Testofen is an herbal extract made from fenugreek seeds. It is known for its ability to support healthy levels of free testosterone. Since this form of testosterone isn’t bound by proteins, your body can use it easily (especially if you’re an older guy) [1].

Zinc

Found in Nugenix Total-T, T-Boost, and Free Testosterone, zinc is a mineral involved in the synthesis of luteinizing hormone.

Also known as LH, it stimulates the production of testosterone in your body and converts it into its active form. By boosting LH and testosterone, zinc may help improve your sexual function [2].

Vitamin B6 and B12

Both of these vitamins are vital to testosterone production, which is why they’re included in T-Boost, Free Testosterone, and Total-T.

B6 plays a role in the actions of testosterone, while B12 is linked to higher serum testosterone concentration and can reduce the risk of testosterone deficiency [3] [4].

L-Citrulline Malate

Does Nugenix work for ED? As one of the ingredients in Free Testosterone, Total-T, and T-Boost, L-citrulline malate could amp up your body’s nitric oxide production. In turn, this can increase blood flow to help fight erectile dysfunction [5].

Tribulus Terrestris

Part of the Total-T Ultimate and Free Testosterone formulas, tribulus terrestris has the potential to uplift testosterone levels, combat fatigue, and support recovery [6].

How Does Nugenix Work?

Nugenix showcases several supplements that are designed to boost men’s T-levels naturally. Let’s talk about three of the most popular ones!

Nugenix Total-T

Featuring l-citrulline, boron, and Tesnor, it aims to boost both free and total testosterone levels. This supplement is also meant to crank up your energy, endurance, and libido.

Nugenix Free Testosterone

As its name suggests, this T-boosting supplement is designed to increase free testosterone, the active form of this male hormone. It does so with ingredients such as fenugreek extract (a.k.a. Testofen), which helps the body use testosterone more effectively, along with zinc and B vitamins.

Nugenix Total-T Ultimate

This formula aims to raise total and free testosterone levels, support lean muscle mass growth, and improve athletic performance. It contains various T-boosting ingredients, including d-aspartic acid, which encourages LH production to signal the testes to make more testosterone [7].

Nugenix Clinical Studies and Evidence

Some ingredients in Nugenix products have been shown individually to raise free testosterone levels in the body. For example:

  • Tesnor, the main ingredient in Nugenix, is a proprietary blend of cocoa and pomegranate peel extract. It was shown to increase free testosterone levels in both low and high dose groups after 7 weeks [8].
  • Boron, while it doesn’t technically raise free testosterone levels, does lower sex hormone-binding globulin (SHBG) levels; thus, it allows more of the free testosterone you already have to roam free [9].
  • ElevATP combines extracts from apple and ancient peat. Although it doesn’t aim to increase testosterone, its goal is to improve athletic performance. In an 8-week study, participants performed better in squats, lifts, and vertical jumps after taking it [10].

Real User Reviews and Testimonials

Does Nugenix work? Find out how actual customers answer this question based on their experience.

According to one 41-year-old user on the official site, he noticed it revved up his energy, stamina, and overall vitality. That’s why he considered Nugenix as a fantastic product [11].

Another 66-year-old user on the official site said the Nugenix testosterone booster has helped him keep his muscles firm and made it possible for him to have lots of sexual activity [12].

One more user on the official site said both he and his wife love that he’s taking Nugenix. Because of it, their love life is like they’re newlyweds again [13].

Another user on Trustpilot also loved the product, yet he wasn’t thrilled with customer service. He lost his subscription that he’s had for years, so he had to go to CVS to get his Nugenix [14].

If you’re still wondering, “Does Nugenix really work?”, Reddit reviews can also be enlightening. For instance, one Redditor shared he’s been using Nugenix for a full 2 months, yet he’s seen no change at all [15].

Pros and Cons of Nugenix

How does Nugenix Total-T work? Let’s weigh its perks and drawbacks!

Pros

  • Contains potent ingredients that boost testosterone, such as Testofen, Tesnor, and zinc
  • 30-day money-back guarantee
  • Subscription option
  • Free gifts for Nugenix orders over $100

Cons

  • More expensive than some competitors
  • Some ingredients may be underdosed compared to studies

Possible Side Effects and Safety Concerns

According to Nugenix, its research has not indicated that its products have any severe side effects. This may be reasonable because its supplements only include natural ingredients.

However, supplements like Nugenix may have different effects on different people. Some users might have a higher tolerance to a product, while a few might have allergic reactions to it.

To be on the safe side, if you are currently taking any prescription medications, have a diagnosed medical condition, or have a history of allergies, talk to your doctor before taking any supplements.

Expert Insights

According to an article on the Low T Center Men’s Healthcare website, Nugenix is not designed to replace low testosterone treatments since it doesn’t involve synthetic testosterone. Testosterone boosters like Nugenix just include vitamins and other natural ingredients [16].

As a multivitamin, it can do some of the things suggested in Nugenix advertising, like raising energy levels and strength, but it won’t necessarily stimulate any testosterone production.

On the other hand, a reviewer on Innerbody shared that three ingredients in Nugenix are research-backed to raise testosterone levels and boost athletic performance. Is it the best testosterone booster for men? He believes there are better products at similar or lower prices [17].

FAQs About Nugenix

Curious to know, “How long does it take for Nugenix to work?” Check out our Q-and-A session below!

How Long Does Nugenix Take To Work?

How long do testosterone pills take to work? Specifically, how fast does Nugenix work? Based on customer reviews on the Walmart site, some users reported results in the first month, while others said it took a few weeks.

Is There a Testosterone Booster That Actually Works?

While many testosterone boosters claim to raise T-levels, they don’t contain synthetic testosterone. Instead, they include vitamins, minerals, and herbs that support your body to create this male hormone. Yet, if you think you’re suffering from low T for medical reasons, consult your doctor and see if you are a good candidate for testosterone therapy.

What Does the FDA Say About Nugenix?

Because it is a dietary supplement and not a prescription drug, Nugenx is not regulated by the FDA. Nugenix Total-T is manufactured under the FDA’s good manufacturing practice guidelines, but that doesn’t guarantee the product’s effectiveness or safety.

Is Nugenix Hard on Your Liver?

Yes, Nugenix may be hard on the liver. Back in 2017, a lawsuit was filed against the company claiming that it caused severe liver damage in a man who then needed a transplant [18].

Does Nugenix Work? In Conclusion

Nugenix is a testosterone supplement that contains ingredients that may help your body produce testosterone. It also aims to boost your energy levels, help increase endurance, and even elevate your libido and sex drive.

On the flip side, it’s pricier than other natural testosterone boosters, and there’s a risk of liver damage in certain users.

Does Nugenix work? At the end of the day, it’s up to you and your doctor to decide whether Nugenix, another testosterone supplement, or testosterone therapy is right for you!

References

  1. Rao, A., Steels, E., Inder, W. J., Abraham, S., & Vitetta, L. (2016). Testofen, a specialized Trigonella foenum-graecum seed extract, reduces age-related symptoms of androgen decrease, increases testosterone levels, and improves sexual function in healthy aging males in a double-blind randomized clinical study. The Aging Male, 19(2), 134–142. https://doi.org/10.3109/13685538.2015.1135323
  2. Jalali, G. R., Roozbeh, J., Mohammadzadeh, A., Sharifian, M., Sagheb, M. M., Jahromi, A. H., Shabani, S., Ghaffarpasand, F., & Afshariani, R. (2010). Impact of oral zinc therapy on the level of sex hormones in male patients on hemodialysis. Renal Failure, 32(4), 417–419. https://doi.org/10.3109/08860221003706958
  3. Symes, E. K., Bender, D. A., Bowden, J. F., & Coulson, W. F. (1984). Increased target tissue uptake of, and sensitivity to, testosterone in the vitamin B6-deficient rat. Journal of Steroid Biochemistry, 20(5), 1089–1093. https://doi.org/10.1016/0022-4731(84)90348-0
  4. Matineh Rastegar Panah, Matineh Rastegar Panah, Matineh Rastegar Panah, & Matineh Rastegar Panah. (2024). Vitamin B12 is associated with higher serum testosterone concentrations and improved androgenic profiles among men with infertility. ˜The œJournal of Nutrition/˜the œJournal of Nutrition. https://doi.org/10.1016/j.tjnut.2024.06.013
  5. Sulyman, A. O., Aliyu, O. M., Ajani, E. O., Abdulkareem, Y. F., Afe, I. A., Abdulyakeen, F. O., Lukman, H. Y., Sabiu, S., Singh, K., & Naidoo, K. (2025). Mechanisms of L-citrulline on phosphodiesterase 5 in erectile dysfunction intervention. Scientific African, 27, e02572. https://doi.org/10.1016/j.sciaf.2025.e02572
  6. Fernández-Lázaro, D., Mielgo-Ayuso, J., del Valle Soto, M., Adams, D. P., González-Bernal, J. J., & Seco-Calvo, J. (2021). The Effects of 6 Weeks of Tribulus terrestris L. Supplementation on Body Composition, Hormonal Response, Perceived Exertion, and CrossFit® Performance: A Randomized, Single-Blind, Placebo-Controlled Study. Nutrients, 13(11), 3969. https://doi.org/10.3390/nu13113969
  7. Topo, E., Soricelli, A., D’Aniello, A., Ronsini, S., & D’Aniello, G. (2009). The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats. Reproductive Biology and Endocrinology, 7(1), 120. https://doi.org/10.1186/1477-7827-7-120
  8. Sreeramaneni PGA, Yalamanchi A, Konda MR, Cherukuri SHV, Maroon JC. A Proprietary Herbal Blend Containing Extracts of Punica granatum Fruit Rind and Theobroma cocoa Seeds Increases Serum Testosterone Level in Healthy Young Males: A Randomized, Double-Blind Placebo-Controlled Study. J Diet Suppl. 2023;20(3):411-427. doi: 10.1080/19390211.2022.2035037. Epub 2022 Feb 6. PMID: 35129040.
  9. Li C, Ford ES, Li B, Giles WH, Liu S. Association of testosterone and sex hormone-binding globulin with metabolic syndrome and insulin resistance in men. Diabetes Care. 2010 Jul;33(7):1618-24. doi: 10.2337/dc09-1788. Epub 2010 Apr 5. PMID: 20368409; PMCID: PMC2890370.
  10. Joy JM, Vogel RM, Moon JR, Falcone PH, Mosman MM, Pietrzkowski Z, Reyes T, Kim MP. Ancient peat and apple extracts supplementation may improve strength and power adaptations in resistance-trained men. BMC Complement Altern Med. 2016 Jul 18;16:224. Doi: 10.1186/s12906-016-1222-x. PMID: 27430755; PMCID: PMC4950767.
  11. Matt M. U.S. (2025) Review of Nugenix on the official site https://www.nugenix.com/reviews
  12. Alberto G. U.S. (2025) Review of Nugenix on the official site https://www.nugenix.com/reviews
  13. Jon B. U.S. (2025) Review of Nugenix on the official site https://www.nugenix.com/reviews
  14. Guy E. Trump U.S. (2025, April 19) Review of Nugenix on Trustpilot https://www.trustpilot.com/review/nugenix.com?stars=3
  15. InfinityScientist U.S. r/supplements Does Nugenix Total T Work (2023) https://www.reddit.com/r/Supplements/comments/vettdn/does_nugenix_total_t_work/
  16. Testosterone Replacement Therapy vs Nugenix Total-T, Low T Center/Reinventing Men’s Healthcare Website (2022, April 8) https://lowtcenter.com/news-article/testosterone-replacement-therapy-vs-nugenix-total-t/
  17. Imperiale, D. (2024, October 25). Nugenix Total-T Reviews. Innerbody; Innerbody Research. https://www.innerbody.com/nugenix-total-t-reviews
  18. Ashna Manhas, Casey Genevieve Arnold, & Allison Marie Bush. (2024). Underreporting Supplements: A Case of Drug-induced Liver Injury Due to a Testosterone Booster. Military Medicine. https://doi.org/10.1093/milmed/usae136